I like the double outline on the germ, nice use of overlapping. The broken box works well. I think it fits under the 'break the grid for emphasis' category.
Been suffering a nagging throat and sinus bug myself.
You've got the bulk of the design in a nice, neat little box (da grid) and the 'colds suck' is popping out of it, thus breaking out of the grid for emphasis upon the fact that colds suck.
I am doing good, thanks. Hope you're feeling better as well.